Precancerous Gastric Lesions with Helicobacter pylori vacA⁺/babA2⁺/oipA⁺ Genotype Increase the Risk of Gastric Cancer

Table 3

Virulence gene in association with clinical outcomes.

Gastric mucosa pathology/Virulence gene	Chronic	Precancerous	OR; 95% CI	value	Precancerous	GC	OR (95% CI)	value
	(n = 44)	(n = 52)			(n = 52)	(n = 70)
VacA	32 (73%)	14 (27%)	2.14 (1.62–4.46)	0.036	14 (27%)	42 (60%)	1.23 (1.13–3.32)	0.033
BabA2	26 (59%)	32 (62%)	0.77 (0.56–0.94)	0.833	32 (62%)	64 (91%)	2.64 (1.44–4.82)	0.024
OipA	12 (27%)	24 (46%)	0.69 (0.49–0.82)	0.546	24 (46%)	64 (91%)	2.79 (1.58–5.41)	0.031

Multivariate regression model analysis used to analyze the data. OR: odds ratio; CI: confidence interval. Significance is set at .