Cholinergic Urticaria: Clinical Presentation and Natural History in a Tropical Country
Table 1
Characteristics and course of cholinergic urticaria in our 16 patients.
Characteristics
Number (%)
Sex
Male
9 (56.3%)
Female
7 (43.7%)
Mean age of onset (yr)
(15, 56)
Mean duration of cholinergic urticaria (yr)
4.9
Associated other urticaria
Chronic spontaneous urticaria
4 (25.0%)
Dermographism
3 (18.8%)
Cold urticaria
2 (12.5%)
Cold urticaria and dermographism
1 (6.3%)
Angioedema
1 (6.3%)
History of anaphylaxis
0
Personal history of atopy
3 (18.8%)
Allergic rhinitis
2 (12.5%)
Asthma
1 (6.3%)
Allergic conjunctivitis
0
Atopic dermatitis
0
Treatment#
sAH1
Hydroxyzine (2)
4 (25%)
nsAH1
Cetirizine (1-2)
7 (43.8%)
Loratadine (1-2)
6 (37.5%)
Fexofenadine (1-2)
12 (75%)
Levocetirizine (1)
1 (6.3%)
Desloratadine (1-2)
2 (12.5%)
Bilastine (2)
2 (12.5%)
AH2
Ranitidine (2)
4 (25%)
Remission (at the time of study)
Yes
6 (37.5%)
No
10 (62.5%)
Mean disease duration (in 6 cases with remission, yr)
(0.3, 13.0)
The data were shown as (minimum, maximum) or number (%). Abbreviations: AH2: H2 receptor antagonist; CSU: chronic spontaneous urticaria; nsAH1: nonsedating H1 antihistamine; sAH1: sedating H1 antihistamine; yr: year. #One patient might have one or more medications. The number of tablets per day.
