Research Article

Identification of Differential Gene Expression Pattern in Lens Epithelial Cells Derived from Cataractous and Noncataractous Lenses of Shumiya Cataract Rat

Table 1

Lists of top 20 genes which are <0.5 downregulated in LECs in 5-week-old Cat+ SCR compared to Cat- SCR.

Gene symbolGene descriptionFC

LgsnLens protein with glutamine synthetase domain0.064
Clic5Chloride intracellular channel 50.094
Snhg11Small nucleolar RNA host gene 110.124
CrygfCrystallin, gammaF0.138
Srd5a2Steriod-5-alpha-reductase, alpha polypeptide 20.165
Cryge| CrygdCrystallin, gamma E| crystallin, gamma D0.185
MipMajor intrinsic protein of lens0.202
HspB1Heat shock protein B10.204
CrygcCrystallin, gamma C0.206
Dnase2BDeoxyribonuclease II beta0.207
LctlLactase-like0.227
Bfsp1Beaded filament structural protein 1, filensin0.231
Clic3Chloride intracellular channel 30.260
Fam89aFamily with sequence similarity 89, member 7A0.272
Cbln2Cerebellin 2 precursor0.273
MallMal, T-cell differentiation protein-like0.281
Wnt7aWingless-type MMTV integration site family, member 7A0.284
Slc24a2Solute carrier family 24 member 30.284
Hmox1Heme oxygenase 10.289
Lpin1Lipin10.302