Identification of Differential Gene Expression Pattern in Lens Epithelial Cells Derived from Cataractous and Noncataractous Lenses of Shumiya Cataract Rat
Table 1
Lists of top 20 genes which are <0.5 downregulated in LECs in 5-week-old Cat+ SCR compared to Cat- SCR.
Gene symbol
Gene description
FC
Lgsn
Lens protein with glutamine synthetase domain
0.064
Clic5
Chloride intracellular channel 5
0.094
Snhg11
Small nucleolar RNA host gene 11
0.124
Crygf
Crystallin, gammaF
0.138
Srd5a2
Steriod-5-alpha-reductase, alpha polypeptide 2
0.165
Cryge| Crygd
Crystallin, gamma E| crystallin, gamma D
0.185
Mip
Major intrinsic protein of lens
0.202
HspB1
Heat shock protein B1
0.204
Crygc
Crystallin, gamma C
0.206
Dnase2B
Deoxyribonuclease II beta
0.207
Lctl
Lactase-like
0.227
Bfsp1
Beaded filament structural protein 1, filensin
0.231
Clic3
Chloride intracellular channel 3
0.260
Fam89a
Family with sequence similarity 89, member 7A
0.272
Cbln2
Cerebellin 2 precursor
0.273
Mall
Mal, T-cell differentiation protein-like
0.281
Wnt7a
Wingless-type MMTV integration site family, member 7A