A Static Magnetic Field Inhibits the Migration and Telomerase Function of Mouse Breast Cancer Cells

Figure 2

SMF treatment accelerated proliferation and inhibited migration of 4T1 cells. (a) Cell numbers counted following SMF exposure to different magnetic fields for 24, 48, and 72 h (h). (b) The proliferation rates of 4T1 cells shown by CFSE fluorescence ratio of SMF/GMF at 24 and 48 h of exposure. (c) Representative images of the wound width and (d) migration efficiency of the SMF and GMF cell at 0 and 24 h of the exposure in the wound healing assay. Wound healing assays and Transwell assays (e) were used to detect the migration ability of cells. (e) Representative fluorescent images showing the nuclei (blue, stained by Hoechst) of the migrated cells exposed in GMF and SMF for 24 h. (f) Compared to the GMF group, SMF treatment significantly inhibited cell migration. Data are the from three independent experiments (). ; ; , compared to the GMF group. SMF: static magnetic field; GMF: geomagnetic field.

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