β-Sitosterol Alleviates Inflammatory Response via Inhibiting the Activation of ERK/p38 and NF-κB Pathways in LPS-Exposed BV2 Cells

Figure 7

The effect of BS on the mRNA expression of proinflammatory mediators in primary microglia. The cells were pretreated with BS for 2 h prior to the exposure of LPS (100 ng/mL); after 12 h, the cells were collected and the mRNA levels of proinflammatory mediators (IL-6 (a), TNF-α (b), iNOS (c), and COX-2 (d)) were tested by real-time PCR. The results were presented as (). ^## versus the control group. and versus the LPS-stimulated group.

(a)

(b)

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(d)