Development and Validation of an Immune-Related Prognostic Signature for Ovarian Cancer Based on Weighted Gene Coexpression Network Analysis

Table 2

The univariate and multivariate Cox regression analysis of the signature with clinical characteristics predictive of overall survival in ovarian cancer in TCGA cohort.

Variable	Overall survival
	Univariate		Multivariate
	HR	value	HR	value
Signature (low-risk vs. high-risk)	0.438	<0.001	0.575	<0.001
Lymphatic invasion (invasion vs. noninvasion)	1.422	0.114
Grade (G3-G4 vs. G1-G2)	1.181	0.054
Clinical stage (stage III-IV vs. stage I-II)	1.660	0.003	1.602	0.026
Tumor residual disease (visible macroscopic vs. no macroscopic)	2.295	<0.001	1.775	0.006
Venous invasion (noninvasion vs. invasion)	0.971	0.910
Age (old age vs. young age)	1.342	0.015	1.286	0.050