Research Article
Development and Validation of an Immune-Related Prognostic Signature for Ovarian Cancer Based on Weighted Gene Coexpression Network Analysis
Table 3
Relationship of clinical characteristics of ovarian cancer patients and signature in TCGA cohort.
| | Characteristics | High-risk () | Low-risk () | value |
| | Age | | | 0.528 | | Mean (years) | | | | | Stage | | | 0.033 | | I | 4 | 11 | | | II | 9 | 16 | | | III | 202 | 208 | | | IV | 48 | 30 | | | NA | 3 | 1 | | | Grade | | | 0.123 | | G1 | 5 | 1 | | | G2 | 40 | 27 | | | G3 | 214 | 232 | | | G4 | 0 | 1 | | | NA | 7 | 5 | | | Residual tumor size | | | <0.001 | | No macroscopic | 36 | 70 | | | 1-10 mm | 134 | 100 | | | 11-20 mm | 20 | 14 | | | >20 mm | 55 | 45 | | | NA | 21 | 37 | | | Lymphatic invasion | | | 0.067 | | Yes | 75 | 57 | | | No | 31 | 47 | | | NA | 160 | 163 | | | Venous invasion | | | 0.003 | | Yes | 52 | 34 | | | No | 22 | 45 | | | NA | 192 | 187 | | | KPS | | | 0.058 | | 40 | 0 | 2 | | | 60 | 7 | 8 | | | 80 | 13 | 27 | | | 100 | 2 | 5 | | | NA | 244 | 224 | | | Therapy outcome | | | 0.006 | | Complete remission/response | 133 | 165 | | | Partial remission/response | 40 | 20 | | | Progressive disease | 24 | 12 | | | Sable disease | 14 | 16 | | | NA | 55 | 53 | | | Neoplasm cancer status | | | 0.002 | | With tumor | 184 | 150 | | | Tumor free | 50 | 85 | | | NA | 32 | 31 | | | New neoplasm event type | | | 0.081 | | Locoregional disease | 5 | 1 | | | Metastatic | 1 | 0 | | | Progression of disease | 12 | 15 | | | Recurrence | 143 | 121 | | | NA | 105 | 129 | |
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