The Effect of Different Treatment Regimens and Multiple Risk Factors on Adverse Pregnancy Outcomes among Syphilis-Seropositive Women in Guangzhou: A Retrospective Cohort Study
Table 2
Comparison of demographic and clinical characteristics between pregnant women with syphilis who were included and excluded in this study (, %).
Characteristics
Included subjects ()
Excluded subjects ()
value
value
Mother’s age in years ()
-4.59
<0.001
Marital status
Married
3018 (86.9)
801 (79.0)
38.42
<0.001
Unmarried
456 (13.1)
213 (21.0)
Ethnicity
Han
3250 (93.6)
917 (90.4)
11.49
0.001
Others
224 (6.5)
97 (9.6)
Educational attainment
Bachelor or above
413 (13.2)
78 (7.7)
57.06
<0.001
High school
872 (27.8)
272 (26.8)
Middle school
1484 (47.3)
463 (45.7)
Primary school or below
367 (11.7)
201 (19.8)
Employed
Yes
973 (34.8)
293 (28.9)
11.65
0.001
No
1824 (65.2)
721 (71.1)
Migrant resident
No
1084 (31.2)
182 (18.0)
68.09
<0.001
Yes
2390 (68.8)
832 (82.1)
Primipara
Yes
1230 (35.4)
508 (50.1)
71.41
<0.001
No
2244 (64.6)
506 (49.9)
History of APOs
No
3202 (92.2)
880 (86.8)
27.67
<0.001
Yes
272 (7.8)
134 (13.2)
History of syphilis infections
No
2017 (58.1)
672 (66.3)
22.04
<0.001
Yes
1457 (41.9)
342 (33.7)
Maternal syphilis stage
Latent
2729 (78.6)
743 (73.3)
14.89
0.001
Stages I-III
184 (5.3)
55 (5.4)
Unknown
561 (16.2)
216 (21.3)
Current syphilis status (partner)
Negative
855 (24.6)
192 (28.1)
7.21
0.027
Positive
241 (6.9)
59 (8.6)
Unknown
2378 (68.5)
433 (63.3)
Log2 titers of TRUST before treatment ()
-0.92
0.358
APOs included spontaneous abortion, stillbirth, and preterm birth. SD: standard deviation; TRUST: toluidine red unheated serum test.