Research Article

The Effect of Different Treatment Regimens and Multiple Risk Factors on Adverse Pregnancy Outcomes among Syphilis-Seropositive Women in Guangzhou: A Retrospective Cohort Study

Table 2

Comparison of demographic and clinical characteristics between pregnant women with syphilis who were included and excluded in this study (, %).

CharacteristicsIncluded subjects ()Excluded subjects () value value

Mother’s age in years ()-4.59<0.001
Marital status
 Married3018 (86.9)801 (79.0)38.42<0.001
 Unmarried456 (13.1)213 (21.0)
Ethnicity
 Han3250 (93.6)917 (90.4)11.490.001
 Others224 (6.5)97 (9.6)
Educational attainment
 Bachelor or above413 (13.2)78 (7.7)57.06<0.001
 High school872 (27.8)272 (26.8)
 Middle school1484 (47.3)463 (45.7)
 Primary school or below367 (11.7)201 (19.8)
Employed
 Yes973 (34.8)293 (28.9)11.650.001
 No1824 (65.2)721 (71.1)
Migrant resident
 No1084 (31.2)182 (18.0)68.09<0.001
 Yes2390 (68.8)832 (82.1)
Primipara
 Yes1230 (35.4)508 (50.1)71.41<0.001
 No2244 (64.6)506 (49.9)
History of APOs
 No3202 (92.2)880 (86.8)27.67<0.001
 Yes272 (7.8)134 (13.2)
History of syphilis infections
 No2017 (58.1)672 (66.3)22.04<0.001
 Yes1457 (41.9)342 (33.7)
Maternal syphilis stage
 Latent2729 (78.6)743 (73.3)14.890.001
 Stages I-III184 (5.3)55 (5.4)
 Unknown561 (16.2)216 (21.3)
Current syphilis status (partner)
 Negative855 (24.6)192 (28.1)7.210.027
 Positive241 (6.9)59 (8.6)
 Unknown2378 (68.5)433 (63.3)
Log2 titers of TRUST before treatment ()-0.920.358

APOs included spontaneous abortion, stillbirth, and preterm birth. SD: standard deviation; TRUST: toluidine red unheated serum test.