Research Article
Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in Murraya koenigii: Deciding Factor of Its In Vitro and In Vivo Efficacies against Cancer Cells
Figure 2
Antiproliferative activities of mahanine, mahanimbine, and koenimbine isolated from MEFWB against ovarian cancer as determined by the MTT assay (a, b). Ovarian cancers cells were exposed to varying concentrations of purified mahanine, mahanimbine, and koenimbine separately for 48 h. IC50 was calculated as the percentage relative to untreated cells which were considered as 100%. Antiproliferative activity of mahanine against PA1 and OVCAR3 by MTT assay has earlier been reported [8]; here, we have repeated this experiment for comparison with mahanimbine and koenimbine. These data were derived from three individual experiments, and mean ± SD was indicated.
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