Research Article

Influence of Geographical and Seasonal Variations on Carbazole Alkaloids Distribution in Murraya koenigii: Deciding Factor of Its In Vitro and In Vivo Efficacies against Cancer Cells

Table 6

In vivo efficacy of MEFTN in tumor xenograft models.

GroupsOvarian (PA1)Lung (A549)
Tumor size (mm3) after the treatment period

Untreated354 ± 7.1426 ± 60
MEFTN89 ± 15170 ± 43

Xenograft models were generated in nude mice. MEFTN (300 mg/kg BW p.o. BID) was fed orally in treated groups, and vehicle was fed to the untreated group for 31 days in ovarian and 14 days in lung cancer. Mean ± SD was indicated in the result.