Research Article

Procalcitonin Identifies Bacterial Coinfections in Vietnamese Children with Severe Respiratory Syncytial Virus Pneumonia

Table 1

Patients’ characteristics between patients with RSV pneumonia alone and RSV pneumonia with bacterial coinfections.

RSV alone ()RSV with bacterial coinfections () value

Age (months) ()0.67
Male, (%)29 (49.2)7 (63.6)0.38
Clinical features
 Fever22 (37.3)9 (81.8)<0.01
 Rapid pulse rate32 (54.2)6 (54.6)0.99
 Runny nose16 (27.1)3 (27.3)0.99
 Wheezing53 (89.8)9 (81.8)0.44
 Diarrhea14 (23.7)2 (18.2)0.69
Vital signs ()
 Respiratory rate (/min)0.87
 Pulse rate (/min)0.83
 Body temperature (°C)<0.01
 SpO20.82
Initial laboratory findings (median, IQR)
 WBC (×103/mm3)9.5 (7.1-12.1)11.2 (5.4-17.3)0.62
 Lymphocyte (%)4.6 (2.9-6.3)3.4 (2.2-9.0)0.46
 Procalcitonin (ng/ml)0.3 (0.1-1.1)2.3 (0.2-4.2)<0.01
 High-sensitivity C-reactive protein (mg/dl)1.5 (0.6-4.9)5.7 (1.7-23.6)0.04
 PaO269.0 (50.0-82.0)64.9 (54.0-92.0)0.99
 Interleukin-6 (pg/ml)2.0 (1.5-6.1)12.4 (3.0-82.8)0.07
Deaths after hospitalization, (%)0 (0.0)2 (18.2)<0.01

SD: standard deviation; SpO2: oxygen saturation; WBC: white blood cell.