Research Article

Procalcitonin Identifies Bacterial Coinfections in Vietnamese Children with Severe Respiratory Syncytial Virus Pneumonia

Table 2

Accuracy of diagnostic parameters regarding different cut-off points.


Sensitivity0.73 (0.39-0.94)0.55 (0.23-0.83)0.63 (0.25-0.92)0.25 (0.03-0.65)0.64 (0.31-0.89)
Specificity0.63 (0.49-0.75)0.92 (0.81-0.97)0.85 (0.72-0.94)0.98 (0.89-1.00)0.73 (0.60-0.84)
Positive predictive value (PPV)0.28 (0.17-0.68)0.55 (0.33-0.83)0.42 (0.15-0.72)0.67 (0.26-0.92)0.30 (0.19-0.67)
Negative predictive value (NPV)0.93 (0.75-0.96)0.92 (0.73-0.97)0.93 (0.81-0.99)0.89 (0.44-1.00)0.92 (0.73-0.95)
Positive likelihood ratio (LR+)1.95 (1.19-3.19)6.44 (2.38-17.45)4.29 (1.80-10.20)12.00 (1.23-117.41)2.35 (1.27-4.33)
Negative likelihood ratio (LR-)0.44 (0.16-1.16)0.50 (0.26-0.95)0.44 (0.18-1.08)0.77 (0.51-1.15)0.50 (0.23-1.11)
Accuracy64.3%84.3%82.1%87.5%70.0%

PCT: procalcitonin; hs-CRP: high-sensitivity C-reactive protein; IL-6: interleukin-6.