Interactions of Consanguinity and Number of Siblings with Childhood Acute Lymphoblastic Leukemia

Table 2

Characteristics of ALL in children in Syria.

Characteristic	Count ()	Percentage (%)
Main presenting symptom
Constitutional symptoms	137	75.7
Lymphadenopathy	20	11
Hepatosplenomegaly	5	2.8
Bruising	13	6.7
Accidental	6	3.3
Missing	12
Hepatosplenomegaly:
Positive	133	72.7
Negative	50	27.3
Missing	10
Lymphadenopathy
Positive	158	81.9%
Negative	33	17.1%
Missing	2
WBC when diagnosed
1500 and less	5	2.6
1500–11 500	87	45.5
11 500 and above	99	51.8
Missing	2
Haemoglobin levels when diagnosed
11–16	23	12
11–7	101	52.6
7 and less	68	35.4
Missing	1
Platelets count
More than 400 000	4	2.1
150 000 to 400 000	21	11.1
150 000 to 50 000	60	31.6
50 000 to 20 000	58	30.5
Less than 20 000	47	24.7
Missing	3
CXR
Mediastinal enlargement or lymphadenopathies	32	16.6
Negative	135	80.8
Missing	26
ALL subtype
B ALL	151	79.9
T ALL	38	20.1
Missing	4
CD 10
81% and more	97	57.1
21% -80%	36	21.2
20% and less	37	21.8
Missing	23
Prognostic risk
Standard	91	51.4
High	86	48.6
Missing	16
FAB classification
L1	90	62.9%
L2	53	37.1%
Missing	50

WBC count of 1500- cells/L, haemoglobin level of 11-16 g/dL, and platelet counts of 150 000- cells/L were considered normal.