Double-Targeted Knockdown of miR-21 and CXCR4 Inhibits Malignant Glioma Progression by Suppression of the PI3K/AKT and Raf/MEK/ERK Pathways

Figure 2

miR-21 and CXCR4 levels of stable glioma cells transfected with anti-miR-21, sh-CXCR4, or anti-miR-21 + sh-CXCR4. (a, b) miR-21 and CXCR4 levels in the transfected U251 and U87 cells were measured using qRT-PCR. (c, d) CXCR4 protein levels in the transfected U251 and U87 cells were measured using western blot. (e) miR-21 and CXCR4 levels in the transfected U251 and U87 cells were measured using qRT-PCR. (f, g) CXCR4 protein levels in the transfected U251 and U87 cells were measured using western blot. .

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