Thyroid Function in 35 Patients with Gitelman Syndrome

Table 2

Comparison of the general characteristics of patients with GS and PA.

	GS	Hypokalemic PA	Normokalemic PA
	35	528	108
Age (years)	^†‡	^‡
Sex (M/F)	16/19	229/299	37/71
Serum K^+ (mmol/L)	^†‡	^‡
Serum Mg^2+(mmol/L)	^†‡
Renin activity (ng/mL/h)	12.00 (12.0, 12.0)^†‡	0.1 (0.1, 0.3)	0.1 (0.1, 0.2)
Angiotensin II (ng/L)	110.7 (88.3, 177.4)^†‡	57.8 (48.1, 68.3)	57.8 (51.8, 66.0)
Aldosterone (ng/dL)	20.8 (15.7, 28.8)^†‡	30.2 (21.3, 38.6)^‡	16.8 (14.3, 20.6)
TSH (mU/L)	2.4 (1.8, 4.8)	2.6 (1.7, 4.0)	2.3 (1.5, 3.2)
TGAb (positive/)	2/20	21/202	6/33
TPOAb (positive/)	3/23	26/211	5/33
TRAb (positive/)	0/19	7/128	0/23

GS: Gitelman syndrome; PA: primary aldosteronism; serum K⁺: serum potassium; TSH: thyroid-stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; TPOAb: thyroid peroxidase antibody; TGAb: thyroglobulin antibody; TRAb: thyrotropin receptor antibody. ^† compared with hypokalemic PA; ^‡ compared with normokalemic PA; compared across groups.