JAK3 and TYK2 Serve as Prognostic Biomarkers and Are Associated with Immune Infiltration in Stomach Adenocarcinoma

Table 4

Correlation analysis between JAK3 and gene biomarkers of immune cells in STAD (TIMER).

Description	Biomarkers	STAD
		None		Purity
		Cor	value	Cor	value
CD8+ T cell	CD8A	0.7		0.684
	CD8B	0.553		0.539
T cell (general)	CD3D	0.711		0.696
	CD3E	0.735		0.73
	CD2	0.701		0.685
B cell	CD19	0.658		0.648
	CD79A	0.629		0.605
Monocyte	CD86	0.562		0.536
	CD115(CSF1R)	0.541		0.527
TAM	CCL2	0.441		0.404
	CD68	0.318		0.294
	IL10	0.482		0.45
M1 macrophage	INOS (NOS2)	0.135		0.129
	IRF5	0.401		0.378
	COX2(PTGS2)	0.036	0.465	0.006	0.915
M2 macrophage	CD163	0.482		0.466
	VSIG4	0.389		0.382
	MS4A4A	0.474		0.451
Neutrophils	CD66b (CEACAM8)	0.054	0.269	0.053	0.307
	CD11b (ITGAM)	0.563		0.554
	CCR7	0.725		0.708
Natural killer cell	KIR2DL1	0.283		0.261
	KIR2DL3	0.264		0.217
	KIR2DL4	0.301		0.268
	KIR3DL1	0.29		0.268
	KIR3DL2	0.433		0.396
	KIR3DL3	0.103		0.103
	KIR2DS4	0.283		0.253
Dendritic cell	HLA-DPB1	0.581		0.556
	HLA-DQB1	0.466		0.418
	HLA-DRA	0.496		0.471
	HLA-DPA1	0.495		0.464
	BDCA-1(CD1C)	0.52		0.482
	BDCA-4(NRP1)	0.472		0.454
	CD11c (ITGAX)	0.64		0.625
Th1	T-bet (TBX21)	0.753		0.753
	STAT4	0.759		0.757
	STAT1	0.466		0.487
	IFN-g (IFNG)	0.438		0.429
	TNF-a (TNF)	0.361		0.322
Th2	GATA3	0.633		0.625
	STAT6	0.296		0.321
	STAT5A	0.581		0.576
	IL13	0.214		0.218
Tfh	BCL6	0.426		0.413
	IL21	0.384		0.362
Th17	STAT3	0.455		0.467
	IL17A	0.075	0.12	0.087	0.0919
Treg	FOXP3	0.711		0.679
	CCR8	0.657		0.644
	STAT5B	0.534		0.545
	TGFb (TGFB1)	0.536		0.52
T cell exhaustion	PD-1 (PDCD1)	0.725		0.718
	CTLA4	0.645		0.623
	LAG3	0.608		0.597
	TIM-3 (HAVCR2)	0.567		0.545
	GZMB	0.449		0.407

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