JAK3 and TYK2 Serve as Prognostic Biomarkers and Are Associated with Immune Infiltration in Stomach Adenocarcinoma

Table 5

Correlation analysis between TYK2 and gene biomarkers of immune cells in STAD (TIMER).

Description	Biomarkers	STAD
		None		Purity
		Cor	value	Cor	value
CD8+ T cell	CD8A	0.298		0.318
	CD8B	0.161		0.166
T cell (general)	CD3D	0.214		0.233
	CD3E	0.295		0.32
	CD2	0.257		0.278
B cell	CD19	0.296		0.309
	CD79A	0.231		0.242
Monocyte	CD86	0.213		0.219
	CD115(CSF1R)	0.302		0.296
TAM	CCL2	0.039	0.432	0.028	0.586
	CD68	0.267		0.265
	IL10	0.288		0.286
M1 macrophage	INOS (NOS2)	0.17		0.165
	IRF5	0.37		0.363
	COX2(PTGS2)	0.009	0.858	0	1
M2 macrophage	CD163	0.31		0.304
	VSIG4	0.159		0.152
	MS4A4A	0.18		0.174
Neutrophils	CD66b (CEACAM8)	0.018	0.713	0.028	0.591
	CD11b (ITGAM)	0.411		0.413
	CCR7	0.31		0.331
Natural killer cell	KIR2DL1	0.036	0.463	0.055	0.283
	KIR2DL3	0.037	0.448	0.046	0.372
	KIR2DL4	0.158		0.178
	KIR3DL1	0.114	0.02	0.128	0.0126
	KIR3DL2	0.145		0.151
	KIR3DL3	0.094	0.0554	0.114
	KIR2DS4	0.09	0.0673	0.104
Dendritic cell	HLA-DPB1	0.26		0.274
	HLA-DQB1	0.249		0.271
	HLA-DRA	0.263		0.278
	HLA-DPA1	0.259		0.269
	BDCA-1(CD1C)	0.175		0.159
	BDCA-4(NRP1)	0.26		0.244
	CD11c (ITGAX)	0.393		0.404
Th1	T-bet (TBX21)	0.372		0.397
	STAT4	0.31		0.33
	STAT1	0.373		0.393
	IFN-g (IFNG)	0.24		0.265
	TNF-a (TNF)	0.254		0.255
Th2	GATA3	0.218		0.235
	STAT6	0.435		0.438
	STAT5A	0.546		0.561
	IL13	0.101	0.039	0.118	0.0213
Tfh	BCL6	0.232		0.233
	IL21	0.216		0.211
Th17	STAT3	0.457		0.456
	IL17A	0.057	0.25	0.068	0.189
Treg	FOXP3	0.439		0.467
	CCR8	0.372		0.379
	STAT5B	0.493		0.489
	TGFb (TGFB1)	0.288		0.293
T cell exhaustion	PD-1 (PDCD1)	0.411		0.448
	CTLA4	0.322		0.347
	LAG3	0.27		0.296
	TIM-3 (HAVCR2)	0.306		0.314
	GZMB	0.159		0.174

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