Sulfonamide-Based Azaheterocyclic Schiff Base Derivatives as Potential Carbonic Anhydrase Inhibitors: Synthesis, Cytotoxicity, and Enzyme Inhibitory Kinetics

Table 2

Kinetic parameters of the compound 3c on carbonic anhydrase.

Concentration (μM)	(ΔA/min)	(mM)	Inhibition type	(μM)
0.00	0.016505745	0.42	Noncompetitive	8.6
7.1	0.010063181	0.42
14.2	0.004551758	0.42
28.4	0.002292984	0.42

is the Michaelis-Menten constant, is the reaction velocity, and is the EI dissociation constant.