Research Article

Hyperbranched Cationic Glycogen Derivative-Mediated IκBα Gene Silencing Regulates the Uveoscleral Outflow Pathway in Rats

Table 2

Grouping and treatment of animals.

GroupTreatmenta

PBS groupPBS
DMAPA-Glyp groupDMAPA-Glyp solution containing 25 μg of DMAPA-Glyp
DMAPA-Glyp+NC groupDMAPA-Glyp and NC-siRNA complex containing 25 μg of DMAPA-Glyp and 5 μg of NC-siRNA
siRNA groupIκBα-siRNA solution containing 5 μg of IκBα-siRNA
Lipo+siRNA groupLipofectamine™ 2000 and IκBα-siRNA complex containing 1.5 μl of Lipofectamine™ 2000 and 5 μg of IκBα-siRNA
DMAPA-Glyp+siRNA groupDMAPA-Glyp and IκBα-siRNA complex containing 25 μg of DMAPA-Glyp and 5 μg of IκBα-siRNA

aIntracameral injection with a volume of 10 μl per eye. Abbreviations: PBS—phosphate-buffered saline; DMAPA-Glyp—3-(dimethylamino)-1-propylamine-conjugated glycogen; NC-siRNA—nonspecific control siRNA; Lipo—Lipofectamine™ 2000.