Association of Toll-Like Receptor 4 Gene Polymorphisms with Acute Aortic Dissection in a Chinese Han Population
Table 1
Baseline characteristics of the study participantsa.
Variables
Control ()
AAD ()
Age (years)
0.769
Male, (%)
163 (73.4%)
164 (73.9%)
0.914
Obesity
0.081
Yes, (%)
42 (18.9%)
54 (24.3%)
No, (%)
173 (77.9%)
146 (65.8%)
Missing, (%)
7 (3.2%)
22 (9.9%)
Smoking
0.089
Yes, (%)
81 (36.5%)
73 (32.9%)
No, (%)
112 (50.4%)
143 (64.4%)
Missing, (%)
29 (13.1%)
6 (2.7%)
Drinking
0.065
Yes, (%)
71 (31.9%)
61 (27.5%)
No, (%)
122 (55.0%)
155 (69.8%)
Missing, (%)
29 (13.1%)
6 (2.7%)
Hypertension
<0.001
Yes, (%)
93 (41.9%)
176 (79.3%)
No, (%)
129 (58.1%)
46 (20.7%)
Diabetes
<0.001
Yes, (%)
23 (10.4%)
82 (36.9%)
No, (%)
199 (89.6%)
126 (56.8%)
Missing, (%)
—
14 (6.3%)
Dyslipidemia
0.426
Yes, (%)
100 (45.1%)
105 (47.3%)
No, (%)
121 (54.5%)
109 (49.1%)
Missing, (%)
1 (0.4%)
8 (3.6%)
WBC (×109/L)
—
—
CRP (mg/L)
—
—
D-dimer (μg/mL)
—
—
Max. aortic diameter (cm)
—
—
Serum TLR4 levels (ng/mL)
—
—
aDemographic and clinical data for 222 AAD patients and 222 controls were collected from the medical records, and maximal aortic diameters of all cases were assessed by CTA. And serum TLR4 levels in a total of 64 AAD subjects were obtained from our previously published data [18].
