Association of Toll-Like Receptor 4 Gene Polymorphisms with Acute Aortic Dissection in a Chinese Han Population
Table 2
The association of TLR4 polymorphisms with the risk of AAD.
NCBI Ref
Control
AAD
OR (95% CI)
rs10759932
TT
13 (46.4%)
93 (41.9%)
106 (48.4%)
TC
12 (42.9%)
95 (42.8%)
94 (42.9%)
0.297
0.759 (0.453-1.274)
CC
3 (10.7%)
34 (15.3%)
19 (8.7%)
0.036 (0.072)
0.393 (0.164-0.939)
CC+TC vs. TT
0.112
0.673 (0.412-1.098)
CC vs. TC+TT
0.045 (0.090)
0.439 (0.196-0.984)
0.239
0.775
rs11536889
GG
48 (57.1%)
154 (70.3%)
148 (66.7%)
GC
31 (36.9%)
57 (26.0%)
58 (26.1%)
0.934
1.023 (0.590-1.775)
CC
5 (6.0%)
8 (3.7%)
16 (7.2%)
0.598
1.351 (0.441-4.135)
CC+GC vs. GG
0.818
1.063 (0.634-1.780)
CC vs. GC+GG
0.615
1.327 (0.441-3.995)
0.351
0.004
for association was adjusted by age, sex, obesity, smoking, drinking, hypertension, diabetes, and dyslipidemia. NCBI Ref: reference frequencies of these SNPs in the Asian population (NCBI database). : values after Bonferroni correction. The results are in bold if .
