Association of Toll-Like Receptor 4 Gene Polymorphisms with Acute Aortic Dissection in a Chinese Han Population

Table 5

FRPR values for significant results on associations between TLR4 polymorphisms and AAD risk.

Genotype	Number of controls/cases	OR (95% CI)		Statistical power^a	Prior probability^b
					0.25	0.1	0.01	0.001	0.0001
rs10759932
CC vs. TT (overall)	34/19 vs. 93/106	0.393 (0.164-0.939)	0.036	<0.001	0.995	0.998	0.999	1.000	1.000
CC vs. TC+TT (overall)	34/19 vs. 188/200	0.439 (0.196-0.984)	0.045	<0.001	0.996	0.998	0.999	1.000	1.000
CC vs. TC+TT (male)	27/12 vs. 136/150	0.343 (0.133-0.882)	0.026	<0.001	0.993	0.996	0.999	1.000	1.000
TC vs. TT (female)	25/11 vs. 27/39	0.231 (0.071-0.752)	0.015	<0.001	0.987	0.994	0.999	1.000	1.000
CC+TC vs. TT (female)	32/18 vs. 27/39	0.241 (0.082-0.707)	0.010	<0.001	0.981	0.991	0.999	1.000	1.000
rs11536889
GC vs. GG (female)	16/18 vs. 40/33	3.382 (1.051-10.885)	0.041	0.706	0.236	0.392	0.854	0.983	0.998
CC+GC vs. GG (female)	19/25 vs. 40/33	3.043 (1.041-8.900)	0.042	0.705	0.241	0.398	0.857	0.984	0.998
CC vs. GC+GG (interaction with dyslipidemia)	1/8 vs. 113/101	15.229 (1.156-200.621)	0.038	0.897	0.184	0.320	0.811	0.977	0.998

^aThe statistical power was calculated using the number of observations, ORs, and values in this table. ^bThe results are in bold if .