Research Article
[Retracted] CircEIF4G2 Promotes Tumorigenesis and Progression of Osteosarcoma by Sponging miR-218
Figure 5
CircEIF4G2 sponges miR-218. (a and b) Dual-luciferase reporter assays showed that miR-218 decreases the relative luciferase activity of the wild-type circEIF4G2 luciferase plasmid compared with the mutant in both HOS (a) and MG63 (b) cells. (c and d) Overexpression of miR-218 significantly suppressed HOS (c) and MG63 (d) cell proliferation using the CCK-8 assay. (e and f) Overexpression of miR-218 significantly suppressed HOS cell migration (e) and invasion (f) using the Transwell assay. (g and h) Overexpression of miR-218 significantly suppressed MG63 cell migration (g) and invasion (h) using the Transwell assay.
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