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| No. | Gene symbol | Full name | Function |
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| 1 | CDKN2A | Cyclin-dependent kinase inhibitor 2A | Capable of inducing cell cycle arrest in G1 and G2 phases. Acts as a tumor suppressor. Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6 |
| 2 | IGF1R | Insulin-like growth factor 1 receptor | The activated IGF1R is involved in cell growth and survival control. IGF1R is crucial for tumor transformation and survival of malignant cell |
| 3 | MDM2 | MDM2 proto-oncogene | Inhibits p53/TP53- and p73/TP73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Inhibits DAXX-mediated apoptosis by inducing its ubiquitination and degradation |
| 4 | SMAD3 | SMAD family member 3 | Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases |
| 5 | SLC2A1 | Solute carrier family 2 member 1 | Facilitative glucose transporter. This isoform may be responsible for constitutive or basal glucose uptake, has a very broad substrate specificity, and can transport a wide range of aldoses including both pentoses and hexoses |
| 6 | GRM5 | Glutamate metabotropic receptor 5 | Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors |
| 7 | PLCB4 | Phospholipase C beta 4 | The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes |
| 8 | FGFR1 | Fibroblast growth factor receptor 1 | Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation, and migration |
| 9 | UBE2V2 | Ubiquitin conjugating enzyme E2 V2 | Plays a role in the control of progress through the cell cycle and differentiation, plays a role in the error-free DNA repair pathway, and contributes to the survival of cells after DNA damage |
| 10 | TNFRSF10B | TNF receptor superfamily member 10b | Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis |
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