Research Article
Mechanism of Abnormal Chondrocyte Proliferation Induced by Piezo1-siRNA Exposed to Mechanical Stretch
Table 3
Percentage of cells in the blank control group and the lentiviral interference group at different stress times.
| Group name | < diploid (%) | Cell cycle (%) | > tetraploid (%) | G0/G1 | S | G2/M |
| Blank control | 48 h group | 7.89 | 61.90 | 20.80 | 6.37 | 0.48 | Blank control | 24 h group | 4.17 | 71.70 | 13.30 | 8.16 | 1.05 | Blank control | 12 h group | 10.80 | 62.60 | 17.10 | 5.65 | 0.54 | Blank control | 2 h group | 10.90 | 68.70 | 11.50 | 5.31 | 0.19 | Blank control | 0 h group | 16.60 | 64.60 | 27.50 | 4.06 | 2.01 | Piezo1-siRNA | 48 h group | 24.70 | 51.90 | 14.90 | 4.86 | 0.33 | Piezo1-siRNA | 24 h group | 2.34 | 70.20 | 20.10 | 4.85 | 0.18 | Piezo1-siRNA | 12 h group | 6.65 | 78.20 | 8.96 | 4.00 | 0.38 | Piezo1-siRNA | 2 h group | 4.19 | 72.10 | 15.80 | 5.68 | 0.32 | Piezo1-siRNA | 0 h group | 8.22 | 58.10 | 25.00 | 4.61 | 0.83 |
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vs. blank control 0 h group, -test, ; vs. Piezo1-siRNA 0 h group, -test, . |