Research Article

Mechanism of Abnormal Chondrocyte Proliferation Induced by Piezo1-siRNA Exposed to Mechanical Stretch

Table 3

Percentage of cells in the blank control group and the lentiviral interference group at different stress times.

Group name< diploid (%)Cell cycle (%)> tetraploid (%)
G0/G1SG2/M

Blank control48 h group7.8961.9020.806.370.48
Blank control24 h group4.1771.7013.308.161.05
Blank control12 h group10.8062.6017.105.650.54
Blank control2 h group10.9068.7011.505.310.19
Blank control0 h group16.6064.6027.504.062.01
Piezo1-siRNA48 h group24.7051.9014.904.860.33
Piezo1-siRNA24 h group2.3470.2020.104.850.18
Piezo1-siRNA12 h group6.6578.208.964.000.38
Piezo1-siRNA2 h group4.1972.1015.805.680.32
Piezo1-siRNA0 h group8.2258.1025.004.610.83

vs. blank control 0 h group, -test, ; vs. Piezo1-siRNA 0 h group, -test, .