Research Article

Acute and Subchronic Oral Toxicity Study of Polyherbal Formulation Containing Allium sativum L., Terminalia bellirica (Gaertn.) Roxb., Curcuma aeruginosa Roxb., and Amomum compactum Sol. ex. Maton in Rats

Table 10

Mean of the biochemical parameters of group rats which received polyherbal formulation or control after 45 days in the subchronic oral toxicity study.

UnitControlDose
252 mg/kg1,008 mg/kg4,032 mg/kg

Male ()
 Ureamg/dL
 Creatininemg/dL
 Total proteinmg/dL
 Albuming/dL3.62 ± 0.13
 Globuling/dL
 AST (GOT)U/L7945
 ALT (ALT)U/L

Female ()
 UreaMg/dL
 CreatinineMg/dL
 Total proteinMg/dL
 Albuming/dL
 Globuling/dL
 AST (GOT)U/L
 ALT (ALT)U/L

, the significant difference compared to the control group using the one-way ANOVA continued by Tukey’s multiple comparison test.