Research Article

Antioxidant and Antiproliferative Potential of Bioactive Molecules Ursolic Acid and Thujone Isolated from Memecylon edule and Elaeagnus indica and Their Inhibitory Effect on Topoisomerase II by Molecular Docking Approach

Table 3

Hydroxyl radical scavenging activity of ursolic acid and thujone.

Concentration (µg/mL)Hydroxyl radical scavenging activity (% of inhibition)
Ursolic acidThujoneAscorbic acidBHA

2046.59 ± 0.24a26.43 ± 0.51a49.60 ± 0.55a42.75 ± 0.52a
4053.48 ± 0.07b47.02 ± 0.71b61.40 ± 0.41b49.65 ± 0.38b
6060.20 ± 0.33c53.35 ± 0.47c76.43 ± 0.34c60.18 ± 0.75c
8070.51 ± 0.21d56.76 ± 0.30d88.25 ± 0.42d73.15 ± 0.38d
10074.62 ± 0.17e63.34 ± 0.22e94.06 ± 0.60e88.55 ± 0.57e

The values are mean of triplicates with (±) standard deviation (mean ± S.D; n = 3). Different superscript letters (a–e) in column within treatments indicates significant differences (at ) when subject to Tukey’s multiple comparison test.