Investigation of the miRNA and mRNA Coexpression Network and Their Prognostic Value in Hepatocellular Carcinoma

Figure 3

The miRNA-mRNA regulatory network consists of 35 miRNAs and 295 target mRNAs. (a) Regulatory network of upregulated miRNAs and downregulated mRNAs. (b) Regulatory network of downregulated miRNAs and upregulated mRNAs. Triangular nodes, miRNA; elliptical nodes, mRNA; green nodes, downregulation; pink nodes, upregulation; blue nodes, tumor suppressor gene; yellow nodes, oncogenes; purple nodes, at the same time in the list of oncogenes and tumor suppressor genes.

(a)

(b)