Research Article
Study on Genotyping Polymorphism and Sequencing of N-Acetyltransferase 2 (NAT2) among Al-Ahsa Population
Table 1
The allele frequency of
NAT2 polymorphisms among Al-Ahsa population (
).
| | NAT2 allele | Mutation site | Amino acid change | Reference ID | Acetylation status | Allele frequency (95% CI) |
| | NAT4 | — | Wild | — | Fast | 0.295 (0.232-0.362) | | NAT11 | 481C>T | Leu161Leu | rs1799929 | Fast | 0.411 (0.342-0.481) | | NAT12 | 803A>G | Arg268Lys | rs1208 | Fast | 0.510 (0.44-0.581) | | NAT13 | 282C>T | Tyr94Tyr | rs1041983 | Fast | 0.354 (0.287-0.422) | | NAT5 | 341T>C | Ile114Thr | rs1801280 | Slow | 0.427 (0.357-0.497) | | NAT6 | 590G>A | Arg197Gln | rs1799930 | Slow | 0.292 (0.227-0.356) | | NAT7 | 857G>A | Gly286Glu | rs1799931 | Slow | 0.057 (0.024-0.09) | | NAT14 | 191G>A | Arg64Gln | rs1801279 | Slow | 0.010 (-0.0039-0.025) |
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