Study on Genotyping Polymorphism and Sequencing of N-Acetyltransferase 2 (NAT2) among Al-Ahsa Population

Table 3

Observed and expected (by using Hardy-Weinberg equilibrium) frequencies of homozygote heterozygote NAT2 alleles among Al-Ahsa population.

NAT2 allele		Homozygote NAT11	Heterozygote NAT11	NAT2 genotype without NAT11
NAT11	Observed number	22	35	39
	Expected number	16.25	46.5	33.3
	of NAT11 = 5.87; at 1 degree of freedom, value 0.05. Not within Hardy-Weinberg equilibrium.
NAT12		Homozygote NAT12	Heterozygote NAT12	NAT2 genotype without NAT12
	Observed number	30	38	28
	Expected number	25	48	23
	of NAT12 = 4.15; at 1 degree of freedom, value 0.05. Not within Hardy-Weinberg equilibrium.
NAT13		Homozygote NAT13	Heterozygote NAT13	NAT2 genotype without NAT13
	Observed number	13	42	41
	Expected number	12	44	40
	of NAT213 = 0.18; at 1 degree of freedom, value 0.05. Within Hardy-Weinberg equilibrium.
NAT5		Homozygote NAT5	Heterozygote NAT5	NAT2 genotype without NAT5
	Observed number	22	38	36
	Expected number	17.5	47	31.5
	of NAT5 = 3.51; at 1 degree of freedom, value 0.05. Within Hardy-Weinberg equilibrium.
NAT6		Homozygote NAT6	Heterozygote NAT6	NAT2 genotype without NAT6
	Observed number	12	32	52
	Expected number	8.2	39.7	48.2
	of NAT6 = 3.59; at 1 degree of freedom, value 0.05. Within Hardy-Weinberg equilibrium.
NAT7		Homozygote NAT7	Heterozygote NAT7	NAT2 genotype without NAT7
	Observed number	0	11	85
	Expected number	0.32	10.4	85.3
	of NAT7 = 0.35; at 1 degree of freedom, value 0.05. Within Hardy-Weinberg equilibrium.
NAT14		Homozygote NAT14	Heterozygote NAT14	NAT2 genotype without NAT14
	Observed number	0	2	94
	Expected number	0.01	2	94
	of NAT14 = 0.01; at 1 degree of freedom, value 0.05. Within Hardy-Weinberg equilibrium.