Novel Model to Predict the Prognosis of Patients with Stage II–III Colon Cancer

Table 2

Demographic and clinicopathological characteristics of stage II-III colon cancer patients with CAR.

Variables		Low CAR (<0.14)	High CAR (≥0.14)	value
Sex	Male	136	217	0.009
	Female	106	107
Age (median, year)	60 (16-89)	57 (16-88)	62 (19-89)	0.884
Tumour site	Left	131	154	0.120
	Right	111	170
BMI (kg/m^2)	21.3 (8.6-43)	21.2 (8.9-41.3)	21.3 (8.6-43)	0.366
Tumour diameter	5.4 (1-15)	5.4 (2-8)	5.4 (1-15)	<0.001
ASA grade	1	172	123	0.212
	2	122	113
	3	15	21
Comorbidities	Diabetes	23	21	0.225
	Pneumonia	10	18
	Hypertension	22	26
	Heart disease	3	4
Intestinal obstruction	Absent	50	74	0.535
	Present	192	250
PLR	206 (55-1113)	211 (55-355)	200 (134-1113)	<0.001
NLR	3.2 (0.53-196)	3.5 (0.57-193)	3.0 (0.53-196)	0.547
CEA (median, mg/ml)	3.5 (0.2-1500)	3.3 (0.2-1500)	5.4 (0.37-1000)	0.043
CA199 (median, mg/ml)	12 (0-1200)	11.2 (0.10-1200)	13.4 (0.00-1200)	0.672
Postoperative chemotherapy	Absent	209	254	0.015
	Present	33	70
Operation mode	Open	55	115	0.001
	Laparoscopic	187	209
LNDs	19 (1-80)	18 (1-80)	19 (1-56)	0.121
LNM	Absent	131	217
	Present	110	107
T-stage	T1-2	11	19	0.020
	T3	81	131
	T4	150	174
LVI	Absent	149	208	0.522
	Present	93	116
PNI	Absent	98	149	0.192
	Present	144	175

LND: lymph node dissection; LNM: lymph node metastasis; LVI: lymphovascular invasion; PNI: perineural invasion.