Effects of Rhein on Bile Acid Homeostasis in Rats

Figure 4

Multivariate data analysis of bile acid profiles in the serum and liver. The OPLS-DA score plots demonstrated complete separation of the samples between groups in the serum (a) and liver (d). The green points represented the control, while the blue, red, and yellow points represented the 10 mg/kg, 30 mg/kg, and 1,000 mg/kg rhein group, respectively, as shown on the plots. The t1 scores in the serum (b) and liver (e) are shown, respectively, according to the OPLS-DA score plots. The VIP plots of OPLS-DA highlighted the discriminatory species in the serum (c) and liver (f).

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