Research Article

Effects of Rhein on Bile Acid Homeostasis in Rats

Table 1

Concentrations of bile acids in serum and liver after treated rats with rhein for 5 weeks.

ControlRhein
0.01 g/kg0.03 g/kg1 g/kg

Serum (ng/mL)
 T-α-MCA
 TCA
 THDCA
 TDCA
 GUDCA
 GHDCA
 GCDCA
 GDCA
 GCA
 UDCA
 DCA
β-MCA
 CA
 CDCA
Liver (μg/g)
 T-α-MCA
 TCA
 THDCA
 TDCA
 GUDCA
 GHDCA
 GCDCA
 GDCA
 GCA
 UDCA
 DCA
β-MCA
 CA
 CDCA

Data are presented as the concentrations in serum measured using UPLC-MS/MS on 5 rats. , , and , compared with the control group of the same bile acid.