Identify Molecular Mechanisms of Jiangzhi Decoction on Nonalcoholic Fatty Liver Disease by Network Pharmacology Analysis and Experimental Validation

Table 2

The overlapped genes between the target genes of active ingredients and NAFLD-related genes.

No.	Uniprot ID	Gene ID	Gene symbol	Gene full name
1	P54710	486	FXYD2	FXYD domain containing ion transport regulator 2
2	P06396	2934	GSN	Gelsolin
3	P28472	2562	GABRB3	Gamma-aminobutyric acid type A receptor Beta3 subunit
4	P07996	7057	THBS1	Thrombospondin 1
5	P54289	781	CACNA2D1	Calcium voltage-gated channel auxiliary subunit Alpha2delta 1
6	P04818	7298	TYMS	Thymidylate synthetase
7	P17302	2697	GJA1	Gap junction protein alpha 1
8	P55011	6558	SLC12A2	Solute carrier family 12 member 2
9	P07585	1634	DCN	Decorin
10	P08729	3855	KRT7	Keratin 7
11	P14210	3082	HGF	Hepatocyte growth factor
12	P13569	1080	CFTR	CF Transmembrane conductance regulator
13	Q96SL4	2882	GPX7	Glutathione peroxidase 7
14	P13500	6347	CCL2	C-C motif chemokine ligand 2
15	O94925	2744	GLS	Glutaminase
16	P21802	2263	FGFR2	Fibroblast growth factor receptor 2
17	Q99584	6284	S100A13	S100 calcium binding protein A13
18	Q13133	10062	NR1H3	Nuclear receptor subfamily 1 group H member 3
19	P13716	210	ALAD	Aminolevulinate dehydratase
20	P82251	11136	SLC7A9	Solute carrier family 7 member 9
21	Q8N159	162417	NAGS	N-Acetylglutamate synthase
22	P21549	189	AGXT	Alanine-glyoxylate and serine-pyruvate aminotransferase
23	P34896	6470	SHMT1	Serine hydroxymethyltransferase 1
24	Q08828	107	ADCY1	Adenylate cyclase 1
25	O43708	2954	GSTZ1	Glutathione S-transferase zeta 1
26	P51570	2584	GALK1	Galactokinase 1
27	P15104	2752	GLUL	Glutamate-ammonia ligase
28	Q14749	27232	GNMT	Glycine N-methyltransferase
29	P36222	1116	CHI3L1	Chitinase 3 like 1
30	Q8TED1	493869	GPX8	Glutathione peroxidase 8 (putative)
31	P11137	4133	MAP2	Microtubule associated protein 2
32	P00750	5327	PLAT	Plasminogen activator, tissue type
33	Q9H2S1	3781	KCNN2	Potassium calcium-activated channel subfamily N member 2
34	P04181	4942	OAT	Ornithine aminotransferase
35	Q07869	5465	PPARA	Peroxisome proliferator activated receptor alpha
36	P01130	3949	LDLR	Low density lipoprotein receptor
37	P09488	2944	GSTM1	Glutathione S-transferase mu 1
38	P09211	2950	GSTP1	Glutathione S-transferase pi 1
39	Q03181	5467	PPARD	Peroxisome proliferator activated receptor delta
40	P30711	2952	GSTT1	Glutathione S-transferase theta 1
41	P08263	2938	GSTA1	Glutathione S-transferase alpha 1
42	P03956	4312	MMP1	Matrix metallopeptidase 1
43	Q9P2W7	27087	B3GAT1	Beta-1,3-glucuronyltransferase 1
44	O60674	3717	JAK2	Janus kinase 2
45	P08700	3562	IL3	Interleukin 3
46	P12821	1636	ACE	Angiotensin I converting enzyme
47	P00734	2147	F2	Coagulation factor II, thrombin
48	Q8WTV0	949	SCARB1	Scavenger receptor class B member 1
49	P06576	506	ATP5F1B	ATP synthase F1 subunit beta
50	O14594	1463	NCAN	Neurocan
51	P24298	2875	GPT	Glutamic-pyruvic transaminase
52	P01375	7124	TNF	Tumor necrosis factor
53	P37231	5468	PPARG	Peroxisome proliferator activated receptor gamma
54	O00206	7099	TLR4	Toll-like receptor 4
55	P06213	3643	INSR	Insulin receptor
56	P00505	2806	GOT2	Glutamic-oxaloacetic transaminase 2
57	P01584	3553	IL1B	Interleukin 1 beta
58	P05019	3479	IGF1	Insulin-like growth factor 1
59	P41235	3172	HNF4A	Hepatocyte nuclear factor 4 alpha