A Combined Effect of Expression Levels of Obesity-Related Genes and Clinical Factors on Cancer Survival Rate

Table 1

Distribution of obesity genes and their related genes in top 25 over/underexpressed genes.

Query protein	Associated functional protein	Over/underexpressed gene-X
LEP	SOCS3, STAT3, JAK2, IRS1, PTPN1, INS, LEPR, PPARG, GCG, ADIPOQ	BRCA: LEP-1, ADIPOQ-9; COAD: GCG-18
LEPR	IL6, JAK2, PTPN1, SOCS3, STAT3, PRL, IL10, IL2, LEP, PRKAA1	BRCA: LEP-1
PCSK1	REN, CTSE, GCG, INS, GIP, CTSD, POMC, NAPSA, CPE, PCSK1N	THCA: PCSK1N-21; COAD: GCG-18
MC4R	MC1R, CRHR1, POMC, GLP1R, SDC3, AGRP, CRH, GCG, NPS, IAPP	COAD: GCG-18
TMEM18	GNPDA2, SH2B1, FTO, NEGR1, FAIM2, MTCH2, SEC16B, MC4R, KTCD15, BCDIN3D	BLCA: NEGR1-11
KCTD15	TMEM18, NEGR1, SH2B1, GNPDA2, SEC16B, TFAP2B, TFAP2C, TFAP2A, TFAP2E, TFAP2D	UCEC: TFAP2A-2; BLCA: NEGR1-11
NEGR1	O3FAR1, SDC3, MTCH2, PYY, GNPDA2, SIGLEC15, IGLL5, KCTD15, TMEM18, SH2B1	BLCA: NEGR1-11; COAD: PYY-3
GPR120/O3FAR1	GPR84, MC3R, SLC6A14, FFAR3, PCSK1, GCG, FFAR2, FFAR1, GPR1, GNAT3	COAD: GCG-18

The order of over (blue)/underexpressed (red) genes.