The Prognostic Significance of miR-21 Expression among Surgically Resected Hepatocellular Carcinoma Patients: Evidence from a Meta-Analysis and Retrospective Cohort Study

Table 4

The characteristics of the pooled studies.

Study (Ref.)	Country	Ethnicity	Sample size	Method	Cutoff	Results	Score (NOS)	Ref.
Tomimaru Y 2012	Japan	Asian	126	qRT-PCR	Mean: 0.754	OS/RFS	8	[28]
Karakatsanis A 2013	Greece	Caucasian	60	qRT-PCR	3.07-fold of control	OS	7	[27]
Gyongyosi B 2014	Italy	Caucasian	20	qRT-PCR	Median	OS	6	[25]
Wang WY 2014	China	Asian	119	qRT-PCR	Median	OS/DFS	8	[29]
Wang X 2015	China	Asian	97	qRT-PCR	Median	OS	7	[30]
Hu L 2016	China	Asian	32	qRT-PCR	Median	OS	6	[26]
Zhu C 2018	China	Asian	50	qRT-PCR	Median	OS/DFS	8	[16]
Zhou Y 2018	China	Asian	83	qRT-PCR		OS/DFS	6	[31]
Tian X.P 2019	China	Asian	124	qRT-PCR	Median	OS/RFS	8	[18]
Our study	China	Asian	166	qRT-PCR	Median	OS/DFS	7