Pharmacological Properties of a Traditional Korean Formula Bojungchiseup-tang on 3T3-L1 Preadipocytes and High-Fat Diet-Induced Obesity Mouse Model

Figure 4

Effect of BJT on the lipid accumulation in liver tissue of HFD-induced obese mice. At the end of the experimental period, the mouse liver was dissected for macroscopic analysis and subjected to hematoxylin/eosin staining (a). Images are shown at the magnification 100x. Western blot was performed to determine the protein level of PPARγ, C/EBPα, and SRBP1. For clarity, cropped gel images are shown (b). qRT-PCR was performed to determine the mRNA level of PPARγ (c), C/EBPα (d), and SRBP1 (e). The values are represented as . ^#, ^##, and ^### vs. CON; and vs. HFD group; significances were determined using one-way ANOVA followed by a Dunnett’s post hoc test.

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