Research Article

Identification of Core Prognosis-Related Candidate Genes in Chinese Gastric Cancer Population Based on Integrated Bioinformatics

Table 2

The top 15 GO terms of BP, CC, and MF of upregulated and downregulated genes.

Category(A) The top 15 enriched GO terms of upregulated genes
TermCount value

BPExtracellular matrix organization202.12-20
BPCell adhesion229.65-16
BPCollagen fibril organization101.05-13
BPCollagen catabolic process112.79-13
BPSkeletal system development116.47-10
CCExtracellular matrix246.15-23
CCProteinaceous extracellular matrix225.02-21
CCExtracellular region407.52-21
CCExtracellular space371.93-20
CCCollagen trimer135.06-15
MFExtracellular matrix structural constituent123.51-15
MFIntegrity binding91.32-08
MFCalcium ion binding162.27-07
MFExtracellular matrix binding54.00-06
MFHeparin binding84.82-06


Category(B) The top 15 enriched GO terms of downregulated genes
TermCount value

BPDigestion142.25-15
BPXenobiotic metabolic process91.95-07
BPSteroid metabolic process62.27-05
BPCellular aldehyde metabolic process47.82-05
BPOxidation-reduction process152.75-04
CCExtracellular space366.18-10
CCExtracellular exosome485.83-07
CCOrganelle membrane77.91-05
CCApical plasma membrane90.002747
CCBasolateral plasma membrane60.016259
MFOxidoreductase activity89.13-04
MFAryl sulfotransferase activity30.003693
MFAldo-keto reductase (NADP) activity30.005787
MFRetinol dehydrogenase activity30.008306
MFInward rectifier potassium channel activity30.010212

BP: biological process; CC: cellular component; MF: molecular function.