Characterization of the Subchondral Bone and Pain Behavior Changes in a Novel Bipedal Standing Mouse Model of Facet Joint Osteoarthritis

<div>Axial loading led to the subchondral bone collapse. (a) The 3D image of SAP of lumbar 5. (b) 3D micro-CT image of the LFJ subchondral bone between control and bipedal standing mouse models. A series of subchondral bone cavities were visualized in a 6-month long bipedal standing mouse model. (c) Quantitative analysis of the morphological parameters of the subchondral bone change in different groups. 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BioMed Research International

fig4

Figure 4

Figure 4: Characterization of the Subchondral Bone and Pain Behavior Changes in a Novel Bipedal Standing Mouse Model of Facet Joint Osteoarthritis 