Development and In Vivo Characterization of Probiotic Lysate-Treated Chitosan Nanogel as a Novel Biocompatible Formulation for Wound Healing

Table 4

Scores of skin histopathological changes in the animal model of wound healing.

Treatments	Epithelialization	Inflammation	Granulation	Fibrosis
Control	Incomplete	1 (2, 1)	3 (3, 2)	2 (3, 2)
Chitosan	Complete	0 (0, 0)	0 (0, 0)	1 (0, 1)
Lactobacillus fermentum	Complete	0 (0, 0)	1 (0, 1)	1 (0, 1)
Lactobacillus reuteri	Complete	0 (0, 0)	1 (0, 1)	1 (0, 1)
Bacillus subtilis natto	Complete	0 (0, 0)	0 (0, 0)	1 (0, 1)

Scores for tissue histopathological changes are represented as median and quartiles for five random pictures per group. indicates significantly different as compared with the control group ().