Association of the Differences in Average Glandular Dose with Breast Cancer Risk
Table 4
Multivariate logistic regression analysis of the effects of NAGD differences in CC-view and MLO-view FFDM images on breast cancer risk.
Variables
OR
value
95% CI
Univariate analysis
NAGD difference in CC view
4.83
<0.001
3.93, 5.95
NAGD difference in MLO view
6.05
<0.001
4.85, 7.55
Multivariate analysis†
NAGD difference in CC view
2.35
<0.001
1.83, 3.02
NAGD difference in MLO view
3.77
<0.001
2.91, 4.90
Age
1.02
0.014
1.00, 1.04
Age at menarche
1.04
0.141
0.99, 1.09
Menopausal status
1.56
0.002
1.18, 2.06
Age at first birth
1.04
0.005
1.01, 1.07
Parity
0.22
0.001
0.09, 0.52
Family history of breast cancer
0.59
0.108
0.30, 1.13
BI-RADS density
1.11
0.243
0.93, 1.33
The univariate analysis was used to examine the association between the NAGD differences and breast cancer risk. †The multivariate analysis was used to examine the independent contribution of breast cancer risk.