Identification of Core Prognosis-Related Candidate Genes in Cervical Cancer via Integrated Bioinformatical Analysis

Table 2

Gene ontology analysis of differentially expressed genes in cervical cancer.

Expression	Category	Term	Count	%	value	FDR
Up-regulated	GOTERM_BP_DIRECT	GO:0006260~DNA replication	17	26.15384615	2.34-19	3.33-16
	GOTERM_BP_DIRECT	GO:0051301~cell division	19	29.23076923	2.73-16	3.22-13
	GOTERM_BP_DIRECT	GO:0007067~mitotic nuclear division	12	18.46153846	1.53-09	2.18-06
	GOTERM_BP_DIRECT	GO:0000082~G1/S transition of mitotic cell cycle	9	13.84615385	3.62-09	5.16-06
	GOTERM_BP_DIRECT	GO:0007062~sister chromatid cohesion	8	12.30769231	9.91-08	1.41-04
	GOTERM_BP_DIRECT	GO:0006270~DNA replication initiation	6	9.230769231	1.09-07	1.55-04
	GOTERM_CC_DIRECT	GO:0005654~nucleoplasm	42	64.61538462	9.29-19	1.04-15
	GOTERM_CC_DIRECT	GO:0005634~nucleus	47	72.30769231	3.90-12	4.37-09
	GOTERM_CC_DIRECT	GO:0030496~midbody	11	16.92307692	2.43-11	2.73-08
	GOTERM_CC_DIRECT	GO:0000777~condensed chromosome kinetochore	9	13.84615385	6.91-10	7.76-07
	GOTERM_CC_DIRECT	GO:0000776~kinetochore	8	12.30769231	1.33-08	1.50-05
	GOTERM_CC_DIRECT	GO:0005876~spindle microtubule	6	9.230769231	4.45-07	4.99-04
	GOTERM_MF_DIRECT	GO:0005524~ATP binding	23	35.38461538	8.92-09	1.03-05
	GOTERM_MF_DIRECT	GO:0005515~protein binding	55	84.61538462	1.75-08	2.03-05
	GOTERM_MF_DIRECT	GO:0003682~chromatin binding	10	15.38461538	1.37-05	0.015903719
	GOTERM_MF_DIRECT	GO:0003677~DNA binding	19	29.23076923	2.60-05	0.030167688
	GOTERM_MF_DIRECT	GO:0043142~single-stranded DNA-dependent ATPase activity	3	4.615384615	6.05-04	0.699450245
Down-regulated	GOTERM_BP_DIRECT	GO:0008284~positive regulation of cell proliferation	3	37.5	0.01471255	15.73085767
	GOTERM_BP_DIRECT	GO:0045597~positive regulation of cell differentiation	2	25	0.015325148	16.33389401
	GOTERM_BP_DIRECT	GO:0050680~negative regulation of epithelial cell proliferation	2	25	0.023116277	23.66719796
	GOTERM_MF_DIRECT	GO:0008236~serine-type peptidase activity	2	25	0.025837913	21.29783341