The Potential Regulatory Roles of lncRNAs in DNA Damage Response in Human Lymphocytes Exposed to UVC Irradiation

Table 1

Coexpressed genes of lncRNAs function in DDR via p53 signaling pathway.

LncRNAs	Gene symbol	4	8	16	32	64 (J/m^2)	Function
		Fold change
GAS6-AS1	GADD45A	2.28	2.54	1.86	2.08	1.47	DNA damage, cell cycle, apoptosis
LOC338799
GAS6-AS1	ID3	1.10	1.29	1.75	1.49	1.57	DNA damage
LOC644656
GAS6-AS1	TP53I3	3.18	4.23	3.73	2.29	1.82	Cell death
LOC338799
LOC644656
GAS6-AS1	MDM2	3.49	3.35	3.30	2.26	1.21	Cell cycle arrest, apoptosis
LOC338799	BAX	1.71	2.4	2.45	2.46	1.99	Apoptosis
LOC338799	CDKN1A	2.28	3.56	3.04	2.50	1.95	Cell cycle arrest, apoptosis
LOC338799	CDK6	-1.03	-1.25	-1.96	-2.75	-3.46	G1 arrest
LOC338799	ISCU	2.63	3.17	3.62	4.76	4.10	-
LOC338799	LCE1C	3.92	7.72	6.48	9.92	5.15	DNA damage
LOC338799	LCE1F	6.01	9.96	14	20	13.6	DNA damage
USP17L6P	TRIAP1	3.74	6.56	8.69	18.5	13.4	Apoptosis
TERC	MOAP1	1.12	1.18	1.31	1.55	1.65	Cell death, apoptosis
TERC	EIF3D	1.12	1.47	1.51	1.94	1.99	Cell death, apoptosis

Genes in bold show more than 2-fold increase in expression levels in at least three groups.