Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway

<div>Dexmedetomidine (Dex) ameliorated cardiac function following I/R (I/R). The hearts were isolated and underwent 30 min ischemia, followed by 60 min reperfusion. Recovery of left ventricular functional assessments is shown: (a) +dp/dt, (b) -dp/dt, (c) LVDP, and (d) LVEDP. Baseline indicates preischemic values; the rest are minutes of reperfusion. 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BioMed Research International

fig1

Figure 1

Figure 1: Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway 

Figure 1 | Dexmedetomidine Protects against Myocardial Ischemia/Reperfusion Injury by Ameliorating Oxidative Stress and Cell Apoptosis through the Trx1-Dependent Akt Pathway 