Crocin Improves Insulin Sensitivity and Ameliorates Adiposity by Regulating AMPK-CDK5-PPARγ Signaling

Figure 1

Deficiency of AMPKα abolished crocin-induced protective effects on general biochemical profiles in type 2 diabetic mice. Type 2 diabetes was induced in wild type and AMPKα mice using high-fat diet incorporated with STZ injection. The type 2 diabetic mice were treated with crocin or vehicle. (a) Body weight (). (b) Serum TG level (). (c) Serum NEFA level (). (d) Serum TC level (). (e) Serum AST activity (). (f) Serum ALT activity (). , , , .

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