Caspase-1-Dependent Pyroptosis of Peripheral Blood Mononuclear Cells Is Associated with the Severity and Mortality of Septic Patients

Table 3

Areas under the ROC curves for predicting 28-day mortality in septic patients.

Parameter	AUC	Sensitivity (%)	Specificity (%)	95% CI
PBMC pyroptosis	0.79	77.78	70.00	0.68-0.90	<0.01
SOFA score	0.65	50.00	73.64	0.51-0.79	0.04
APACHE II score	0.65	76.47	46.85	0.51-0.78	0.05
PCT	0.68	87.50	56.25	0.55-0.81	0.02
IL-6	0.75	75.00	66.96	0.66-0.83	<0.01

PBMCs: peripheral blood mononuclear cells; SOFA: sequential organ failure assessment; APACHE: acute physiology and chronic health evaluation; PCT: procalcitonin; IL: interleukin; AUC: area under the curve; CI: confidence interval.