Aptamer-Conjugated Multifunctional Polymeric Nanoparticles as Cancer-Targeted, MRI-Ultrasensitive Drug Delivery Systems for Treatment of Castration-Resistant Prostate Cancer

Figure 3

Hysteresis loops of 6 nm SPION (a) and Wy5a-SPIO/Dtxl-NPs (b) measured at 10 K and 300 K. The two insets in the figures showed the local magnification. (c) T2-weighted imaging of Wy5a-SPIO/Dtxl-NPs at the different iron concentration and T2 relaxation rate as a function of the iron concentration of Wy5a-SPIO/Dtxl-NPs.

(a)

(b)

(c)