Isoliquiritigenin Suppressed Esophageal Squamous Carcinoma Growth by Blocking EGFR Activation and Inducing Cell Cycle Arrest

Figure 1

Isoliquiritigenin (ILQ) inhibited ESCC proliferation in vitro. (a) The structure of ILQ, B–D, ILQ inhibited ESCC cell proliferation. KYSE-140 (b), KYSE-520 (c), and TE-1 (d) cells were incubated with different concentrations of ILQ for different times, and cell viability was examined by MTS assay. E–G, ILQ inhibited the anchorage-independent growth of ESCC cells. KYSE-140 (e), KYSE-520 (f), and TE-1 (g) cells were treated with different ILQ, and the colony formation in soft agar was detected as described.

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