Bioinformatical Analysis of miRNA-mRNA Interaction Network Underlying Macrophage Aging and Cholesterol-Responsive Difference between Young and Aged Macrophages

Figure 1

Differentially expressed miRNAs and mRNAs in macrophage aging. The volcano plot (a) and the heat map (b) showed that a total of 14 miRNAs were detected to be differentially expressed; 7 were upregulated and 7 downregulated. The volcano plot (c) and the heat map (d) displayed that 101 miRNAs expressed differentially between aged and young macrophages, and 7 of them were upregulated.

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