Metformin Inhibited Proliferation and Metastasis of Colorectal Cancer and presented a Synergistic Effect on 5-FU

Figure 6

Metformin and the combination of metformin and 5-FU inhibited the metastasis of CRC in vivo. (a). Representative macroscopic images of CRC with or without metastasis. (b). Representative photomicrographs of metastatic carcinoma. The images were observed under a magnification of 100x.

(a)

(b)